"Avidin" Kutató, Fejlesztö és Kereskedelmi Korlátolt Felelösségü Társaság;SONEAS Kutató Korlátolt Felelosségu Társaság
发明人:
Ózsvári, Béla,Fehér, Liliána,Gyuris, Márió,Kanizsai, Iván,Madácsi, Ramóna,Puskás, László,Szabó, Csaba,TAMÁS, Gábor
申请号:
DK11752335
公开号:
DK2566849T3
申请日:
2011.05.06
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
The invention relates to compounds of the general formula (I) and their pharmaceutically acceptable salts (in which formula R1 represents a hydrogen atom, lower alkyl group, lower alkenyl group, lower cycloalkyl group, aryl group, aralkyl group or heterocyclic group, wherein, the above groups are optionally substituted in ortho, meta and/or para position with 1, 2, 3 or 4 electron withdrawing groups or electron donating groups; R2 represents a hydrogen atom, lower alkyl group, aryl group, aralkyl group or heterocyclic group wherein the above groups are optionally substituted with one or more halogen atoms; R3 represents a lower alkyl group, aryl group, aralkyl group or heterocyclic group wherein the above groups are optionally substituted in ortho, meta or para position with 1, 2, 3 or 4 electron withdrawing groups or electron donating groups; R4 represents a hydrogen atom, lower alkyl group or any acidic functional group; n is 1 or 2). The compounds according to the invention can be used in the medicine mainly for the treatment of diseases associated with neurological and/or oxidative stress.