Consejo Superior De Investigaciones Científicas;Universidad Autónoma de Madrid;Fundación Para La Investigación Biomédica Del Hospital De La Princesa
发明人:
申请号:
EP16766331.9
公开号:
EP3333255A1
申请日:
2016.08.08
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention relates to lymphocytes, preferably that have been transinfected from dendritic cells with a bacterium, preferably CD4+ T cells, preferably Listeria monocytogenes, wherein said bacterium comprises a tumor peptide. It also relates to the use of lymphocytes for therapy and/or treatment of solid tumors, preferably melanoma, the kit or device which comprises for this purpose. Furthermore, it also refers to the transinfection method thereof.