Sanofi Biotechnology;Regeneron Pharmaceuticals, Inc.
发明人:
Huang, Xiaohong,Jasson, Martine,Marks, Vanessa,Radin, Allen
申请号:
HRP20180299
公开号:
HRP20180299T1
申请日:
2018.02.19
申请国别(地区):
HR
年份:
2018
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide improved treatment regimens for the improvement of symptoms associated with rheumatoid arthritis.SOLUTION: The present invention provides a method for administering an antibody that specifically binds human interleukin-6 receptor (hIL-6R) or an antigen-binding fragment thereof, and one of the group consisting of methotrexate, leflunomide, sulfasalazine and hydroxychloroquin. Preferably, the method includes administering sarilumab (SAR153191) as an antibody. More preferably, the method includes administering sarilumab and methotrexate together.SELECTED DRAWING: None