An example system is disclosed for generating a model of a tubular anatomical structure. The system includes an anatomical measurement wire (“AMW”), a tracking system and a computing device. The AMW is configured to be navigated through the anatomical structure of a patient, and the AMW includes at least one sensor. The tracking system is configured to provide tracking data representing multiple positions of the sensor in a spatial coordinate system. The computing device is configured to generate a data point cloud based on the tracking data, generate a parametric model corresponding to at least a portion of the vessel based on the data point cloud and store the parametric model in non-transitory memory.