Stable antibody formulation

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专利权人:

Inc.;Regeneron Pharmaceuticals

发明人:

Hu, Qingyan,Liu, Dingjiang

申请号：

AU2018247501

公开号：

AU2018247501A1

申请日:

2018.03.23

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

The present invention provides stable pharmaceutical formulations comprising a human antibody that specifically binds to human programmed death -1 protein (PD-1). In certain embodiments, the formulations contain, in addition to an anti-PD-1 antibody, a buffer, an amino acid, a non-ionic surfactant, and a sugar. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability upon stress and storage.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/