Amphiphilic molecule, molecular assembly containing the same, and use thereof

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专利权人:

学校法人早稲田大学;日本ケミカルリサーチ株式会社

发明人:

武岡 真司,小幡 洋輔,田島 祥二,伊藤 学,水野 篤志,西山 名津子,竹内 良人

申请号：

JP2009515278

公开号：

JP5241711B2

申请日:

2008.05.16

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The present invention provides an amphiphilic molecule having a plurality of zwitterionic functional groups in its hydrophilic moiety and a molecular assembly comprising the amphiphilic molecule as a constituent lipid. According to a preferred embodiment of the present invention, the molecular assembly of the present invention forms a stable vesicular structure under a physiological pH environment to carry a substance of interest in the vesicular structure, and can release the substance of interest to the outside of the vesicular structure when it is deformed under an acidic pH environment. The molecular assembly of the present invention can be used as a carrier for a drug, a probe, a nucleic acid, a protein or the like.

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中国工程科技知识中心

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