Benoit Rene Eugene PINTEUR;Gilles Guy DEVILLERS;GOLDFISH
发明人:
BenoÏtè René Eugène PINTEUR,Gilles Guy DEVILLERS
申请号：
US15029997
公开号：
US20160296610A1
申请日:
2014.10.15
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention describes a method for preparing a composition comprising tumour cell stress proteins, said method comprising the following steps: providing tumour cells in a culture medium； subjecting the tumour cells under i) to a stress with the result that these cells produce stress proteins in response to the stress； obtaining or recovering stressed tumour cells and/or stress proteins； treating the stressed tumour cells and/or the stress proteins obtained with a molecule or a process capable of rendering the stress proteins immunogenic, preferably a hapten or haptenization. The invention also describes a pharmaceutical composition comprising tumour cell stress proteins and/or tumour cells comprising stress proteins, these stress proteins being rendered immunogenic, and are in particular haptenized, and a pharmaceutically acceptable excipient.
