A microponic irrigation system is formed using a plurality a grow tubes, a pressure manifold, and a drainage manifold. Each of the plurality of grow tubes defines a grow chamber within the interior of the grow tube and is provided with at least one cradle assembly to support of a plant disposed with its roots suspended in air within the grow chamber. The pressure manifold fluidly couples a reservoir to each of the plurality of grow tubes and delivers nutrient solution housed in the reservoir to the plurality of grow tubes under pressure. The pressurized nutrient solution delivered to the grow tubes is misted into each grow chamber to be absorbed into the roots of each rooted clone supported in the grow tube. The drainage manifold collects unabsorbed nutrient solution from each of the plurality of grow tubes and circulates the unabsorbed nutrient solution back to the reservoir.