Takumi Kawabe,Naoki Mine,Naoya Saito,Keiichi Sakakibara,Takuji Sato
申请号:
US14313264
公开号:
US09221872B2
申请日:
2014.06.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells. While the invention is not limited to any particular mechanism, the compounds of the invention appear to function at least in part by inhibiting G2 cell cycle checkpoint. Thus, invention compounds can be used to inhibit cell growth alone or be used in combination with a nucleic acid damaging treatment to inhibit cell growth.