USE OF A GENETICALLY MODIFIED INFECTIOUS MEASLES VIRUS WITH ENHANCED PRO-APOPTOTIC PROPERTIES (MV-DELTAC VIRUS) IN CANCER THERAPY

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专利权人:

INSTITUT PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITE DE NANTES

发明人:

Frédéric TANGY,Marc GREGOIRE,Jean-François FONTENEAU,Jean-Baptiste GUILLERME,Chantal COMBREDET

申请号：

US16429571

公开号：

US20200016260A1

申请日:

2019.06.03

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumour or cancer conditions, and for the preparation of agents or compositions for such treatment.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/