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NUCLEIC ACIDS FOR TREATMENT OF ALLERGIES
专利权人:
William Hearl;Teri Heiland
发明人:
William Hearl,Teri Heiland
申请号:
US14407410
公开号:
US20160185831A1
申请日:
2012.06.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides DNA vaccines for the treatment of allergies. The vaccines comprise the coding sequence for one or more allergenic epitopes, and preferably the full protein sequence, of the allergenic protein from which the epitope(s) is derived, fused inframe with the lumenal domain of the lysosomal associated membrane protein (LAMP) and the targeting sequence of LAMP. The vaccines allow for presentation of properly configured three dimensional epitopes for production of an immune response. The vaccines can be multivalent molecules, and/or can be provided as part of a multivalent vaccine containing two or more DNA constructs.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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