(57) SUMMARY The present invention, or formula (I) (II), wherein 0 or 1 n R 2 is either hydrogen hydroxy or R 1 is hydrogen or, when n is 0 forming a secondary bond one bond between carbon atoms 1, R 2 R taken together, n is hydrogen each R 1 and R 2 when 1 and R 2 R 1 R 3 R 4 is alkyl or aryl moiety 4 -COOR -COOH or substituents of the ring D A, B, and often, the other hydrogen, halogen, alkyl, hydroxy, alkoxy and be the same or different and are each I disclose the preparation of piperidine derivative compounds are selected from the substituent. Formula (III), wherein, -CG 1 G 2 G 3, or (IV) Z is (V), and m is 1 is an integer from 6 to one process Y and Q, are the same or different is selected from NR 5 O, and S G 3 and 1, G 2 G are the same or different, is selected from NR 8 R 9 and 8, SR 8 OR X 3 is a halogen, OR 15, SR There in NHSO 2 R 15 or 16, OSO 2 R 15 15, NR 15 R R 7 is the same or different and R 6, from NR 8 R 9 hydrogen, alkyl moiety, aryl moiety, and 8, SR 8 OR R 9 and 5, R 8 R is the same or different, is selected from aryl moiety hydrogen, and alkyl moiety been selected to provide the positional isomers, piperidine derivative compounds with piperidine compound this position isomers It involves converting. Formula (VI), wherein, halogen, triaryl tin or trialkyl, triaryl or trialkyl borate, trialkyl silicon, halo silicon, preparation of another of the piperidine derivative compound, substitution sulfonic acid ester X 1, or provides a α- disubstituted methyl benzene derivatives, having a useful substituent in the organic metal binding reaction α, to be converted to the piperidine derivative compound piperidine compound α- disubstituted methyl benzene derivatives, this α including. Alternatively, (VII), in, X 2 is R 10 is hydrogen and and an amine or a part, has a portion having a halogen, an alkali metal oxide, an expression -OR 10, Equation -SR 10 further have are those selected from the group consisting of aryl portion and alkyl portion 4 provides a
