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Method of treating proliferative disorders and other pathological conditions mediated by Bcr-Abl, c-Kit, DDR1, DDR2 or PDGF-R kinase activity
专利权人:
Novartis AG
发明人:
Gallagher, Neil,Yin, Ophelia
申请号:
AU2010322102
公开号:
AU2010322102B2
申请日:
2010.11.17
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to a regimen for the administration of a pyrimidyl- aminobenzamide of formula (I) wherein the radicals as defined herein, or of a pharmaceutically acceptable salt thereof, for the treatment of proliferative disorders, particularly solid and liquid tumors, and other pathological conditions mediated by the Bcr-Abl oncoprotein, the cell transmembrane tyrosine kinase receptor c-Kit, DDR1 (discoidin domain receptor 1), DDR2 (discoidin domain receptor 2) or PDGF-R (platelet derived growth factor receptor) kinase activity, wherein the pyrimidylaminobenzamide of formula I and, optionally, pharmaceutically acceptable carriers, are dispersed in a fruit preparation.
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