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FOXM1 peptide and medicinal agent comprising the same
专利权人:
Oncotherapy Science; Inc.
发明人:
Yokomine, Kazunori,Nakamura, Yusuke,Nishimura, Yasuharu,Tsunoda, Takuya
申请号:
AU2008290049
公开号:
AU2008290049B2
申请日:
2008.08.12
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The object is to provide a means which enables a cancer immunotherapy for about30% of various types of cancer patients in Japan who express forkhead box M1 (FOXM1)at high levels, by identifying a FOXM1-derived peptide which can bind to HLA-A2to activate a human killer T-cell that can kill a cancer cell. Specifically disclosedis a peptide selected from the following items (A) and (B): (A) a peptide comprisingan amino acid sequence depicted in any one of SEQ ID NOs: 1 to 3; and (B) a peptidewhich has the substitution, deletion, insertion and/or addition of one, twoor several amino acid residues in a peptide comprising an amino acid sequencedepicted in any one of SEQ ID NOs: 1 to 3 and which has an activity of inducing a cytotoxic(killer) T-cell.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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