The United States Govermment - Department of Veterans Affairs;University of Iowa Research Foundation
发明人:
David M. Lubaroff,Delbert L. Harris
申请号：
US16606578
公开号：
US20200121774A1
申请日:
2018.04.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method of vaccinating a subject is provided, where a cancer protective response is produced. A first vaccine comprises an adenovirus vector comprising at least one nucleic acid molecule that produces a cancer protective response is administered, followed by one or more second vaccines comprising an alphavirus replicon particle comprising RNA comprising or produced from the nucleic acid molecule. In an embodiment the cancer is prostate cancer.
