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OXAZOLIDINONE DERIVATIVES AS PPAR LIGANDS
专利权人:
发明人:
Ruth Pérez Fernández,María Nieves Fresno López,José Elguero Bertolini,Pilar Goya Laza,Ana Belén Torres Zaguirre,Fernando Rodíguez De Fonseca,Francisco Javier Pavón Morón,Manuel Macías González,Miguel
申请号:
US14904228
公开号:
US20160152579A1
申请日:
2014.07.11
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a family of differently substituted oxazolidinones and to the pharmaceutically acceptable salts, esters, prodrugs, tautomers, solvates and hydrates thereof, which show affinity for the alpha and gamma subtypes of the peroxisome proliferator-activated receptors (PPAR) and which, therefore, modulate the actions regulated by said receptors, such as inducing satiety, controlling ingestion and modulating metabolic effects, and thus are useful for the administration thereof as a pharmacological tool and as drugs for the treatment and/or prevention of metabolic diseases and cardiovascular diseases.
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