Arthur E. Colvin;Hui Jiang;Arthur E. Colvin, JR.; JR.
发明人:
Arthur E. Colvin, JR.,Hui Jiang
申请号：
US13421013
公开号：
US20120238842A1
申请日:
2012.03.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.
