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MÉTODO PARA PRODUÇÃO DE DERIVADO HETEROCÍCLICO SUBSTITUÍDO POR FENILO POR MEIO DE MÉTODO DE ACOPLAMENTO USANDO UM COMPOSTO DE PALÁDIO
专利权人:
TEIJIN PHARMA LIMITED
发明人:
MASATO KOMIYAMA
申请号:
PT11820025
公开号:
PT2610248T
申请日:
2011.08.26
申请国别(地区):
PT
年份:
2016
代理人:
摘要:
The present invention provides a method for producing a xanthine oxidase inhibitor, which is a therapeutic agent for hyperuricemia, or intermediates of the same, said method being efficient and using a short process. The present invention is a novel coupling method for obtaining a compound represented by formula (3) by bringing about a coupling reaction between a compound represented by formula (1) and a compound represented by formula (2), in the presence of a palladium compound, a ligand capable of coordinating to the palladium compound, a base, a C 1 -C 40 carboxylic acid, and at least one kind of additive.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
masato komiyama
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