The present invention provide a poultice applicator in which a plurality of disposable rubber sponges, cloths or resins are attached to the poultice applicator in advance, used rubber sponges, cloths or resins are removed sequentially, and unused (new) rubber sponges, cloths or resins is used to apply drug to skin. For example, it is provided the analgesic and antiphlogistic poultice and/or the antipruritic and anti-inflammatory poultice may be contained in a poultice applicator, in which a plurality of disposable rubber sponges, cloths or resins are attached to the existing rubber sponge, cloth or resin.