A blood pressure measurement device comprises a case, a first electrode and a stress sensor. The case includes a first surface and a second surface. The first electrode is disposed on the first surface, and the stress sensor is disposed on the second surface. The blood pressure measurement device is operated on a part of a body of a user. The part of the body has a blood vessel inside. Upon measurement of the blood pressure, the first electrode, the stress sensor and the blood vessel at least partially overlap in one projection orientation. Therefore, the stress sensor is able to be pressed on the part of the body when the user touches the first electrode. A method of blood pressure measurement is also disclosed.
