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heterocyclic compound and pharmaceutical composition thereof
专利权人:
LTD.;OTSUKA PHARMACEUTICAL CO.
发明人:
HIDEKI TAKASU,HIRONORI MATSUYAMA,KEISUKE MIYAJIMA,KEIZO KAN,KENJI YOSHIDA,MAKOTO SAKAMOTO,MASATOSHI IIDA,NAOTO OHI,NORIKAZU HASHIMOTO,SHIGEKAZU FUJITA,TAE FUKUSHIMA,TAKASHI NAKAGAWA,TAKUMI SUMIDA,YASH
申请号:
BRPI0819232
公开号:
BRPI0819232A2
申请日:
2008.10.29
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention provides a heterocyclic compound represented by General Formula (1): wherein R1 is a group R5-Z1-, etc., Z1 is a lower alkylene group, etc., and R5 is a group represented by General Formula; wherein R13 is a hydrogen atom, etc., m is an integer from 1 to 5; R2 is a hydrogen atom: Y is CH or N: A1 is a heterocyclic ring selected from the group consisting of indolediyl groups, wherein the heterocyclic ring may have at least one substituent: T is a group -CO-, etc.: R3 is a hydrogen atom, etc.: R4 is a lower alkyl group optionally substituted by one or more hydroxy groups, etc.: R3 and R4, together with the nitrogen atom to which they bind, may bind to each other and form a 5- to 10-membered saturated heterocyclic ring, wherein the heterocyclic ring may have at least one substituent. The heterocyclic compound of the present invention has excellent effects of suppressing the production of collagen and/or treating tumors.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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