The invention concerns an adjuvant composition consisting of or comprising at least one permeate obtained from waste water derived from fungal borne production of at least one pharmaceutically active or additive ingredient using at least one microorganism, in particular a fungal species, a method of producing the adjuvant composition, the use of the adjuvant in agriculture, a plant growth media, the use of the plant growth media and a growth substrate consisting of or comprising the adjuvant composition.