LIM, SE YOUNG,PARK, SUNG HEE,SHIN, RYOUNG AE,CHOI, IN YOUNG,KWON, SE CHANG,林世榮,朴晟喜,申玲愛,崔仁榮,權世昌
申请号：
HK14112891.9
公开号：
HK1199220A
申请日:
2014.12.24
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
The present invention relates to a pharmaceutical composition for the prevention and treatment of non-alcoholic fatty liver disease (NAFLD), including a conjugate prepared by covalently linking an insulinotropic peptide, a non-peptidyl polymer and an immunoglobulin Fc region. The composition of the present invention maintains the in-vivo activity of the peptide at a relatively high level, and remarkably increases the blood half-life, thereby preventing triglyceride accumulation which is a typical feature of non-alcoholic fatty liver disease. Ultimately, it can be desirably employed for the prevention and treatment of non-alcoholic fatty liver disease.
