VALLEJO;CEDENO, DAVID LEONARDO;VALLEJO, RICARDO;BENYAMIN, RASMIN M.; RICARDO
发明人:
VALLEJO, RICARDO,CEDENO, DAVID LEONARDO,BENYAMIN, RASMIN M.
申请号:
CA2983582
公开号:
CA2983582A1
申请日:
2016.03.21
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Apparatus and methods for managing pain uses separate varying electromagnetic fields, with a variety of temporal and amplitude characteristics, which are applied to a particular neural structure to modulate glial and neuronal interactions as a mechanism for relieving chronic pain. In another embodiment, a single composite modulation/stimulation signal which has rhythmically varying characteristics is used to achieve the same results as separate varying electromagnetic fields. Also, disclosed is an apparatus and method for modulating the expression of genes involved in diverse pathways including inflammatory/immune system mediators, ion channels and neurotransmitters, in both the Spinal Cord (SC) and Dorsal Root Ganglion (DRG) where such expression modulation is caused by spinal cord stimulation or peripheral nerve stimulation using the disclosed apparatus and techniques.