It is an object of the present invention to provide a kind of methods for generating with excellent strength and a piece of shape cell structure of shape-maintenance performance, have excellent strength and a piece of shape cell structure of shape-maintenance performance. According to the present invention, provide a kind of method for generating a piece of shape cell structure, it include: the block for adding a biocompatible macromolecular, Unit one, and one liquid medium to have multiple recess portions in a culture surface one culture support object on, be immersed in the block of the biocompatible macromolecular in the upper section of recess portion and a step of unit Unit is cultivated to obtain a step of a piece of shape cell structure.