Targeted sustained release sodium alginate microsphere vascular embolization agent containing sorafenib, its production method and use

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专利权人:

ベイジン シェンイヤオ サイエンス アンド テクノロジー ディベロップメント カンパニー リミテッド

发明人:

リ， シンジァン,ホン， ホン,ル， ギ,リ, シンジァン,ホン, ホン,ル, ギ

申请号：

JP2012505035

公开号：

JP5802193B2

申请日:

2010.04.14

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

A targeted sustained-release microsphere vascular embolizing agent, the production method and the use thereof are disclosed. The microsphere comprises sodium alginate as the carrier and sorafenib as the targeted anti-tumor medicine and sorafenib is encapsulated by sodium alginate. The weight ratio of sorafenib to sodium alginate is 1:1ˆ¼1:30. The microspheres are used for manufacturing medicament for the treatment of solid tumors with advantages induing high medicine concentration in the target regions with reduced systemic dosage and toxic and side effects.

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