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經修飾的微載體及其用途
专利权人:
发明人:
LAI, JUI YANG,赖瑞阳,賴瑞陽,赖孟恒,賴孟恆
申请号:
TW102117358
公开号:
TWI487540B
申请日:
2013.05.16
申请国别(地区):
TW
年份:
2015
代理人:
摘要:
The present invention provides a modified micro-carrier, which is formed by chemical modification with oxidized hyaluronic acid and covering on the surface of a microsphere, wherein the microsphere is formed of gelatin cross-linked with carboxyl groups and amino groups. The present invention also provides a cell delivery system, which contains the aforementioned modified micro-carriers and an attached cell. The present invention further provides an application of using the aforementioned cell delivery system in the preparation of pharmaceutical for the treatment and/or prevention of eye diseases, which is suitable for repairing damaged eye cells by intraocular injection.一種經修飾的微載體,是經氧化的透明質酸透過化學修飾而覆蓋在一微球的表面上所形成,其中,該微球是由羧基與胺基相互交聯的明膠所形成。本發明亦提供一種細胞遞送系統,其包含有一如上所述的經修飾的微載體以及一附著型細胞。本發明另提供一如上所述的細胞遞送系統供應用於製備一用來治療和/或預防眼睛疾病之醫藥品的用途,適用於藉由眼內注射而修復受損的眼睛細胞。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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