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REDUCTION DU TAUX D'AMYLOID BETA DANS DES TISSUES AUTRE QUE LE CERVEAU
专利权人:
MODGENE; LLC
发明人:
申请号:
EP09761084.4
公开号:
EP2365804B1
申请日:
2009.11.13
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to methods and compositions for modulating levels of amyloid-&bgr; peptide (A&bgr;) exhibited by non-neuronal (i.e., peripheral) cells, fluids, or tissues. The invention also relates to modulation of A&bgr; levels via selective modulation (e.g., inhibition) of γ-secretase activity. The invention also relates to methods of preventing, treating or ameliorating the symptoms of a disorder, including but not limited to an A&bgr;-related disorder, by administering a compound that result in the modulation of γ-secretase in a non-neuronal tissue, either directly or indirectly to prevent, treat or ameliorate the symptoms of a brain A&bgr; disorder, such as Alzheimer's disease.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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