Scott B. Hoyt,Min K. Park,Clare London,Yusheng Xiong,D. Jonathan Bennett,Jaiqiang Cai,Paul Ratcliffe,Andrew Cooke,Emma Carswell,John MacLean,Rohit Saxena,Bheemashankar A. Kulkarni,Archana Gupta
申请号:
US13811059
公开号:
US20130317057A1
申请日:
2011.07.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention involves compounds of structural Formula (I) and the pharmaceutically acceptable salts thereof. The compounds of the invention are effective at selectively inhibiting CYP11B2, and are therefore useful for the treatment or prophylaxis of disorders that are associated with elevated aldosterone levels, including, but not limited to, hypertension and heart failure.