Industry-Academic Cooperation Foundation, Yonsei University;Emory University;The UAB Research Foundation
发明人:
Young-Sup Yoon,Shin-Jeong Lee,Ho-Wook Jun
申请号：
US15805894
公开号：
US20180127713A1
申请日:
2017.11.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This disclosure relates to methods of generating endothelial cells derived from stem cells. In certain embodiments, the cells are useful for inducing vasculature in muscles and cardiac tissue. In certain embodiments, the disclosure relates to methods of transforming pluripotent or multipotent stem cells, such as embryonic or induced pluripotent stem cells, into endothelial cells derived therefrom using a GSK3 inhibitor and/or delta like canonical notch ligand 4 (DLL4).
