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DERIVES DE PHENYLE UTILISES EN TANT QUE MODULATEURS DES RECEPTEURS DES PGE2
专利权人:
IDORSIA PHARMACEUTICALS LTD
发明人:
BOSS, CHRISTOPH,CORMINBOEUF, OLIVIER,FRETZ, HEINZ,LYOTHIER, ISABELLE,POZZI, DAVIDE,RICHARD-BILDSTEIN, SYLVIA,SIENDT, HERVE,SIFFERLEN, THIERRY
申请号:
CA3060597
公开号:
CA3060597A1
申请日:
2018.05.17
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to phenyl derivatives of formula (I) Formula (I)wherein (R1)n, R3, R4a , R4b , R5b and Ar1are as described in the description and their use in the treatment of cancerby modulating an immune response comprising a reactivationof the immune system in the tumor. The invention further relates to novelbenzofurane and benzothiophene derivatives of formula (III)and their use as pharmaceuticals, to their preparation, to pharmaceuticallyacceptable salts thereof, and to their use as pharmaceuticals,to pharmaceutical compositions containing one or more compounds of formula(I), and especially to their use as modulators of theprostaglandin 2 receptors EP2 and/or EP4.(see formula I)
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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