The present invention relates to novel antigen binding proteins, in particular monoclonal antibodies, capable of binding to the protein Axl as well as the amino and nucleic acid sequences coding for said proteins. From one aspect, the invention relates to novel antigen binding proteins, or antigen binding fragments, capable of binding to Axl and, by inducing internalization of Axl, being internalized into the cell. The invention also comprises the use of said antigen binding proteins as addressing products in conjugation with other anti-cancer compounds, such as toxins, radio-elements or drugs, and the use of same for the treatment of certain cancers.本發明係有關於能夠結合至蛋白Axl之新穎的抗原結合蛋白,特別是單株抗體,以及編碼該蛋白之胺基酸和核酸序列。由一個態樣,本發明係有關於新穎的抗原結合蛋白或抗原結合片段,其能結合Axl以及,透過誘導Axl之內化,而被內化至細胞之內。本發明亦包含該抗原結合蛋白結合其他的抗癌化合物,例如毒素、放射性元素或藥物,來作為定址產物之用途,以及該抗原結合蛋白用於治療某些癌症之用途。
