PRESIDENT AND FELLOWS OF HARVARD COLLEGE;IMMUNE DISEASE INSTITUTE;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;THE BRIGHAM AND WOMEN'S HOSPITAL INC.
发明人:
申请号：
IL24044415
公开号：
IL240444D0
申请日:
2015.08.09
申请国别(地区):
IL
年份:
2015
代理人:
摘要：
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or in B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at least one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one vaccine nanocarrier to a subject in need thereof.
