<；P>；PROBLEM TO BE SOLVED: To provide an uricase preparation utilizable for medicines, cosmetics, hair-dyeing agents, etc. and to particularly provide an uricase preparation having a composition enabling storage and distribution at a temperature not lower than ordinary temperature (15-25°；C according to JIS) as well as storage and distribution in refrigeration and especially to provide uricase preparation which is stable even at high temperature under water-soluble conditions. <；P>；SOLUTION: The present invention provides an uricase preparation containing a protein having uricase activity as an active ingredient, having active optimum temperature at 35-45°；C close to body temperature and having extremely high stability. <；P>；COPYRIGHT: (C)2008,JPO&INPIT
