KOREA YAKULT CO., LTD.;주식회사한국야쿠르트; LTD.;KOREA YAKULT CO.
发明人:
PARK, SE HOON,박세훈,LEE, HO YONG,이호용,ANH, YOUNG TAE,안영태,IM, SIN HYEOG,임신혁,HUH, CHUL SUNG,허철성
申请号:
KR1020110109764
公开号:
KR1020130045511A
申请日:
2011.10.26
申请国别(地区):
KR
年份:
2013
代理人:
摘要:
PURPOSE: Lactobacillus helveticus HY7801 which prevent rheumatoid arthritis and a product containing the same are provided to enhance expression of IL-10 which is an anti-inflammatory cytokine, and to reduce expression of IL-12 which is an inflammatory cytokine. CONSTITUTION: Lactobacillus helveticus HY7801(deposit number KCTC 11959BP) prevents rheumatoid arthritis by increasing expression of a Foxp3(Forkhead box p3) transcriptional regulator of regulatory T cells(Tregs). A pharmaceutical composition for preventing rheumatoid arthritis contains the strain as an active ingredient. Fermented milk, functional drink, and health functional food contain the strain as an active ingredient.본 발명은 류마티스 관절염 예방 효능을 갖는 락토바실러스 헬베티쿠스(Lactobacillus helveticus) HY7801 및 이를 유효성분으로 함유하는 제품에 관한 것으로서, 류마티스 관절염을 비롯한 염증성 질환의 치료 및 예방과 더불어 항염증 효능을 위한 약학적 조성물, 발효유, 건강기능 식품 등으로 이용될 수 있다.