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Test strips for determining coagulation factor activities
专利权人:
CGT Enterprises, LLC
发明人:
Galmés Sureda Bernat,Canaro Hirnyk Mariana Isabel,Cortina Giner Vicente R.
申请号:
US201414891119
公开号:
US9651567(B2)
申请日:
2014.02.21
申请国别(地区):
美国
年份:
2017
代理人:
Wilson Sonsini Goodrich & Rosati
摘要:
Test strips for determining the activity of a coagulation factor in a blood sample are provided. The strip comprises a support, a sample inlet port for deposition of a blood sample, and a reaction area comprising a blood coagulation reagent. The sample inlet port is connected to the reaction area, and the coagulation reagent comprises blood plasma deficient in the coagulation factor for which activity is to be measured, an ionic citrate source an ionic calcium source, and either one or more coagulation contact phase activator reagents and phospholipids or a mixture of tissue factor and phospholipids. The disclosure further relates to in vitro methods for measuring an activity of a coagulation factor.
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