The present invention provides a therapeutic drug for hyperparathyroidism, renal osteodystrophy, hypercalcemia and the like, which has the action of activating CaSR( or the agonism of CaSR).A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof is provided:[wherein, the partial structure, Ar, of the compound of general formula (I) represents phenyl or naphthyl； R1aand R1brepresent the same or different hydrogen atom, halo etc.； R2aand R2brepresent the same or different hydrogen atom, halo etc.； A represents a single bond, oxygen atom etc.； B represents a single, C1~C4 alkandiyl etc.； Z represents carboxy or tetrazole； m represents an integer of 1~3].本發明提供具有CaSR活性化(激動)作用的副甲狀腺機能亢進症、腎性骨營養不良、高鈣血症等之治療藥。下述之一般式(1)所代表之化合物或其藥理上可容許的鹽：[式中，一般式(1)中之部分構造之Ar表示苯基或萘基；R1a及R1b為相同或相異之氫原子、鹵素基等；R2a及R2b表示相同或相異之氫原子、鹵素基等；A表示單鍵、氧原子等；B為單鍵、C1～C4烷二基等；Z表示羧基或四唑基；m表示1～3之整數]。
