LEE, DONG WOOK,이동욱,KIM, SUN OH,김선오,NA, JU RYUN,나주련,OH, KYO NYEO,오교녀,BAE, DONG HYUCK,배동혁,CHOI, EUN JIN,최은진,JUNG, MYUNG A,정명아,PARK, SANG UN,박상언,CHOI, CHUL YUNG,최철웅,KIM, JAE GAP,김재갑
申请号：
KR1020110084693
公开号：
KR1012289200000B1
申请日:
2011.08.24
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A composition containing a Dendropanax morbifera leaf extract is provided to promote bowel movement and to treat intestinal diseases such as constipation. CONSTITUTION: A pharmaceutical composition for preventing and treating functional constipation or organic constipation contains a Dendropanax morbifera leaf extract as an active ingredient. The extract is prepared using water, low carbon number Ca-C4 alcohol, or a mixture solvent thereof. Functional constipation includes atonic constipation or spastic constipation. Organic constipation includes stenosis of intestine, sigmoid colon, or megasigmoid. A health functional food for preventing and treating functional constipation or organic constipation contains the extract as an active ingredient. A food additive for preventing and treating functional constipation or organic constipation contains the extract as an active ingredient. [Reference numerals] (AA) Control group； (BB) Low dietary fiber intake group； (CC) Low dietary fiber + dendropanax morbifera leaf extract 100mg/kg； (DD) Low dietary fiber + dendropanax morbifera leaf extract 300mg/kg； (EE) Low dietary fiber + dendropanax morbifera leaf extract 500mg/kg； (FF) Weight of excrement(before drying)； (GG) Weight of excrement(after drying)； (H1,H2) Negative control group； (I1,I2) Dendropanax morbifera leaf extract 100mg/kg； (J1,J2) Dendropanax morbifera leaf extract 300mg/kg； (K1,K2) Dendropanax morbifera leaf extract 500mg/kg본 발명은 황칠나무 잎 추출물을 함유하는 조성물에 관한 것으로, 황칠나무 잎을 다양한 용매를 이용하여 추출, 농축하여 수득 가능한 분말 또는 엑기스를 포함하는 장 운동능력 활성화를 통한 변비와 같은 장질환의 예방 및 치료를 위한 약학조성물 및 건강기능식품에 관한 것으로, 본 발명에 의한 황칠나무 잎 추출물은 랫트에서 장 운동 촉진, 정장효과 및 변비개선효과가 탁월함을 확인하였다. 본 발명의 황칠나무 잎 추출물은 장 운동능력 활성화에 따른 변비와 같은 장질환의 예방 및 치료를 위한 약학조성물 및 건강기능식품으로 유용하게 이용될 수 있다.
