The present invention relates to a method for producing a biopharmaceutical product comprising a biomolecule of interest, said method comprising: (a) a first phase of preparing a drug substance of the biomolecule of interest, wherein said first phase comprises (a1) collecting (A2) purification, (a3) rebuffering, and (a4) enrichment, wherein said at least one processing step in said first phase comprises at least three amino acids. Carried out in the presence of a substance, wherein the combination of at least three amino acids has at least one positively charged functional group, at least one antioxidant functional group, at least one osmotic pressure regulating function, and at least one buffering function. Providing a first phase, and (b) a second phase for further processing the drug substance prepared in (a) to obtain a biopharmaceutical product, wherein said second phase comprises (b1) rebuffering； b C.) At least one processing step selected from: freezing, (b3) thawing, and (b4) filling, wherein said at least one processing step in this second phase comprises: (i) at least three amino acids； At least three amino acids, wherein the combination of at least three amino acids provides at least one positively charged functional group, at least one antioxidant functional group, at least one osmotic pressure adjusting function, and at least one buffering function； and (Ii) a second phase carried out in the presence of a composition comprising one or more sugars, wherein the ratio of amino acids to sugars is from 10: 1 to 1: 100 (w / w). The invention further relates to a biopharmaceutical product obtained or obtained by the method of the invention.本発明は目的の生体分子を含む生物医薬製品を生産する方法に関し、前記方法は（ａ）目的の生体分子の原薬を調製する第１相であって、前記第１相が（ａ１）採取、（ａ２）精製、（ａ３）再緩衝化、および（ａ４）濃縮から選択される少なくとも１つの処理ステップを含み、この第１相における前記少なくとも１つの処理ステップが、少なくとも３つのアミノ酸を含む組成物の存在下で行なわれ、前記少なくとも３つのアミノ酸の組合せが、少なくとも１つの正に荷電した官能基、少なくとも１つの抗酸化官能基、少なくとも１つの浸透圧調整機能、および少なくとも１つの緩衝機能を提供する、第１相、および（ｂ）（ａ）で調製された原薬をさらに処理して生物医薬製品を得る第２相であって、前記第２相が（ｂ１
