Provided is a pharmaceutical composition that is effective against various β-lactamase-producing bacteria. The present invention provides a pharmaceutical composition characterized by comprising a combination of (a) a compound represented by formula (I), or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt and (b) at least one component selected from the group consisting of: (i) ceftazidime, or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt, and avibactam, or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt； (ii)ceftolozane, or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt, and tazobactam, or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt； (iii) fosfomycin, or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt； (iv) avibactam, or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt, and pyridine 2,6-dicarboxylic acid, or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt； (v) ampicillin, or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt； and sulbactam, or a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the pharmaceutically acceptable salt.L'invention concerne une composition pharmaceutique qui est efficace contre diverses bactéries productrices de β-lactamase. La présente invention concerne une composition pharmaceutique caractérisée en ce qu'elle comprend une combinaison de (a) un composé repré
