The invention relates to alternating pressure devices with temperature and humidity regulation, specifically the device of the present invention is applicable to the prevention of pressure ulcers, in the preferred use thereof. The invention comprises a first control volume, a second control volume adjacent to the first control volume and independent from the first control volume, a pressurised flow source, a first flow inlet connected to the first control volume and to the pressurised flow source, a second flow inlet connected to the second control volume and to the pressurised flow source, a fluid release mechanism with a matrix of fluid outflow pores, a third flow inlet connected to the fluid release mechanism and to the pressurised fluid source and a control unit, where the control unit controls the fluid release mechanism, and the inflation and the deflation of the control volumes alternating the first control volume and the second control volume, and the vector that orients the pores of the pore matrix is not normal to the contact surface of the human body so that the flow is continuous through the pores and to reduce the flow obstructions caused by the direct contact of the body with the pore.La presente invención se relaciona con los dispositivo de presión alternante con regulación de temperatura y humedad, específicamente el dispositivo de la presente invención en su uso preferido se aplica a la prevención de las ulceras por presión. La presente invención comprende un primer volumen de control, un segundo volumen de control adyacente al primer volumen de control e independientemente del primer volumen de control, una fuente de flujo a presión, una primera entrada de flujo conectada al primer volumen de control y a la fuente de flujo a presión, una segunda entrada de flujo conectada al segundo volumen de control y conectada a la fuente de flujo a presión, un mecanismo de liberación de fluido con una matriz de poros de salida de fluido, una tercera entrada de