SINOCHEM CORPORATION;SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD.
发明人:
Changling Liu,Baoshan Chai,Huichao Li,Aiying Guan
申请号:
US14376074
公开号:
US09376376B2
申请日:
2013.03.06
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to substituted diphenylamine compounds using as antitumor agents. The structure of the compounds is represented as the general formula (I):The groups are as defined as specification.The compound represented by formula (I) showed potent antitumor activity, especially to cure or alleviate the cancer causing by cancer cells of human tissue or organ. The preferred cancers are: colon cancer, liver cancer, lymph cancer, lung cancer, esophageal cancer, breast cancer, central nervous system cancer, melanoma, ovarian cancer, cervical cancer, renal cancer, leukemia, prostatic cancer, pancreatic cancer, bladder cancer, rectal cancer, osteosarcoma, nasopharynx cancer or stomach cancer.