Formulations and methods are disclosed which are effective to kill or control bacteria in the nares including gram-positive bacteria strains of that are antibiotic resistant (MRSA - methicillin-resistant . A preferred composition comprises one or more medium-chain alcohols (dodecanol), glycerol monoesters (glycerol monocaprylate or glycerol monolaurate), and/or benzoic acid or benzoic acid analog, in a suitable pharmaceutical carrier, preferably an ointment, along with an odorant compound, preferably eucalyptus oil. The formulations and variations of the formulation may also be used on open wounds or lesions as well as intact skin.