This invention relates to quaternary ammonium compound for use as an inhibitor of protein kinase C alpha, of formula I: wherein: R 1 is selected from the group of alkyl, alkene, aryl or alkylaryl group preferably R 1 is a benzyl, alkylbenzyl or alkylphenyl group more preferably benzyl or methylphenyl group optionally substituted by hydroxyl, oxo, nitro, amido, carboxy, amino, cyano, alkoxy, alkyl, alkene, alkyne, ester or heteroalkyl group. R 2 is an alkyl chain comprising at least 12 carbon atoms preferably comprising 14, 16 or 18 carbon atoms R 3 or R 4 are identical or different and each is selected from an alkyl chain preferably a C1-C4 alkyl chain more preferably is methyl group. X - is selected from an anion of a pharmaceutically acceptable acid or from halo group preferably X - is selected from halo group more preferably is Cl - or Br - . In particular, the present invention relates to a long-chain quaternary ammonium of formula (I) as a wound healing and/or an anti-inflammatory agent for use in the treatment of eye conditions.
