Disclosed is the use of a composition comprising non-digestible oligosaccharides, a composition comprising at least one Bifidobacterium selected from the group consisting of B. Longum, B. Breve, B. infantis, B. catenulatum, B. pseudocatenulatum, B. adolescentis, B. animalis, B. gallicum, B. lactis and B. Bifidum, and a composition comprising at least a second Bifidobacterium selected from the group consisting of B. longum, B. breve, B. infantis, B. catenulatum, B. pseudocatenulatum, B. adolescentis, B. animalis, B. gallicum, B. lactis and B. Bifidum, and/or long-chain polyunsaturated fatty acids selected from the group consisting of eicosapentaenoic acid, docosahexaenoic acid and arachidonic acid, for the manufacture of a composition for treatment and/or prevention of a disorder in infants delivered via caesarean section, wherein the disorder is selected from the group consisting of allergy, asthma, infection and atopic dermatitis. also disclosed are compositions comprising non-digestible oligosaccharides and bifidobacteria