Acid Derivatives benzoazepin - Oxy acid as agonists of peroxisome proliferator activated receptor Delta used to increase high density lipoprotein cholesterol, low density lipoprotein, reduce cholesterol and reduce
Demarest, Keith T,Pelton, Patricia,Zhang, Yan,Gee-Hong, Kuo,Shen, Lan,Lu, Songfeng
申请号：
NO20084847
公开号：
NO344334B1
申请日:
2008.11.18
申请国别(地区):
NO
年份:
2019
代理人:
摘要：
The invention is directed to compounds of Formula (I) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertension, ischemia, stroke, irritable bowel disorder, inflammation, cataract, cardiovascular diseases, Metabolic X Syndrome, hyper-LDL-cholesterolemia, dyslipidemia (including hypertriglyceridemia, hypercholesterolemia, mixed hyperlipidemia, and hypo-HDL-cholesterolemia), atherosclerosis, obesity, and other disorders related to lipid metabolism and energy homeostasis complications thereof, using compounds of the invention are also described.
