Formula compound (I) is disclosed in this document,2.1.1.8.1.2.2.2.2.2 and r1-r8 have any meaning defined in this document and can be accepted on drugs. In addition, pharmaceutical compounds containing formula (I) compounds and methods of use thereof are disclosed, including formula compounds (I),and pharmaceutically acceptable salts there of,wherein R1-R8 have any of the meanings defined here. In addition, the disclosed pharmaceutical ingredients of formula (I) and methods of using the sameSe desvelan en el presente documento compuestos de Fórmula (I), y sales farmacéuticamente aceptables de los mismos, en la que R1-R8 tienen cualquiera de los significados definidos en el presente documento. Además, se desvelan composiciones farmacéuticas que comprenden compuestos de Fórmula (I) y métodos de uso de los mismos.Disclosed herein are compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R8 have any of the meanings defined herein. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of using the same.