A syringe (100) comprising a barrel (1), a needle holder (12) that holds a hypodermic needle (14) through a needle opening (102), and a hollow plunger (6), wherein the needle holder (12) is biased away from the needle opening (102) such that when the hollow plunger (6) moves through the injection stroke the needle holder (12) is propelled by the biasing member (13) to retract into the hollow plunger (6).