Biocompatible synthetic or natural scaffolds are provided for thereconstruction, repair, augmentation or replacement of organs or tissuestructures in a patient in need of such treatment. The scaffolds are shaped toconform to at least a part of the organ or tissue structure and may be seededwith one or more cell populations. Inserts, receptacles and ports are alsoprovided for the attachment of tubular vessels to the neo-organ scaffolds. Theseeded scaffolds are implanted into the patient at the site in need oftreatment to form an organized organ or tissue structure. The scaffolds may beused to form organs or tissues, such as bladders, urethras, valves, and bloodvessels.