您的位置: 首页 > 农业专利 > 详情页

POSTOPKI ZA PRIPRAVO AMINOALKIL FENILKARBAMATOV
专利权人:
GENERICS (UK) LIMITED
发明人:
GAITONDE ABHAY,MANGLE MANGESH,PAWAR SANJAY R.,GAITONDE Abhay,MANGLE Mangesh,PAWAR Sanjay R.
申请号:
SI200432282
公开号:
SI1697313T1
申请日:
2004.12.17
申请国别(地区):
SI
年份:
2016
代理人:
摘要:
A process according to Scheme One wherein R1 to R5 are any atom or group, including the possibility that R1 and R2 and/or R3 and R4 together with the N to which they are attached form a ring. In particular, R1, R3, R4 and R5 are each methyl, R2 is ethyl and product 5 is obtained as a hydrogen tartrate salt, the product then being rivastigmine hydrogen tartrate. The process has the advantage of avoiding the preparation of zwitterionic intermediates which are very water soluble and need to be isolated by concentration of aqueous solvent. The process is therefore suited to industrial scale manufacture of aminoalkyl phenylcarbamates. The large amounts of sulfated ash residues left in the product when prepared by prior art processes and the use of pyrophoric and hazardous reagents such as sodium hydride may be avoided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充